Curriculum vitae

Professional Experience

    • July 2012 to present:  Freelance Science Writer, Editor, and Microbiology Consultant
    • Aug 2012 to present: Research Scholar, Ronin Institute
    • Feb 2011 to Feb 2015: Content Reviewer for American Journal Experts
    • Jan 2013 to Dec 2014: co-creator of Life in Our Phage World book
    • Jan 2013 to Apr 2013: Instructor for Advanced Molecular Biology, Wilfrid Laurier University
    • Jan 2009 to June 2012: Postdoctoral fellow in the laboratory of Dr. David S. Guttman, Dept. Cell & Systems Biology, U. of Toronto
    • June 2006 to Dec 2008: Postdoctoral Fellow in the laboratory of Dr. Rosemary J. Redfield, Dept of Zoology, U. of British Columbia

Education

    • May 2006: Ph.D. in Ecology & Evolutionary Biology (Minor: Genetics), University of Arizona
    • Aug 1999: B.S. in Biology , Utah State University

Continuing Education

    • 2012: The Freelance Writing Business, University of Toronto School of Continuing Studies
    • 2008: Computational Phyloinformatics course, National Evolutionary Synthesis Center
    • 2007: Linear Models in R workshop
    • 2006: Grants 101:Professional Grant Proposal Writing Workshop
Expertise Ecology & Evolutionary Biology, Genetics & Genomics, Metagenomics, Microbiology
Scientific publications:
Life in Our Phage World: A centennial field guide to the Earth's most diverse inhabitants.  

Created by Forest Rohwer, Merry Youle, Heather Maughan, Nao Hisakawa, Leah Pantea, and Benjamin Darby. PDFs are freely available or a stunningly beautiful print copy can be purchased from Amazon. 

Published articles, news clips, and technical documents:
Publications in peer-reviewed journals:
    1. Haas, A.F., M.F.M Fairoz, L.W. Kelly, C.E. Nelson, E.A. Dinsdale, R.A Edwards, S. Giles, M. Hatay, N. Hisakawa, B. Knowles, Y.W. Lim, H. Maughan, O. Pantos, T.N.F. Roach, S.E. Sanchez, C.B. Silveira, S. Sandin, J.E. Smith, and F. Rohwer. 2016. Global microbialization of coral reefs. Nat. Microbiol. 1:16042. doi:10.1038/nmicrobiol.2016.42.
    2. Hisakawa, N., S.D. Quistad, E.R. Hester, D. Martynova, H. Maughan, E. Sala, M.V. Gavrilo, and F. Rohwer. 2015. Metagenomic and satellite analyses of red snow in the Russian Arctic. PeerJ 3:e1491; DOI 10.7717/peerj.1491.
    3. Murren, C.J., J.R. Auld, H. Callahan, C.K. Ghalambor, C.A. Handelsman, M.A. Heskel, J.G. Kingsolver, H.J. Maclean, J. Masel, H. Maughan, D.W. Pfennig, R.A. Relyea, S. Seiter, E. Snell-Rood, U.K. Steiner, and C.D. Schlichting. 2015. Constraints on the evolution of phenotypic plasticity: limits and costs of phenotype and plasticity. Heredity. doi:10.1038/hdy.2015.8.
    4. Fajardo-Cavazos, P., H. Maughan, and W.L. Nicholson. 2014. Evolution in the Bacillaceae. Microbiol Spectrum 2(5). 
    5. Whiteson, K.L., V. Lazarevic, M. Tangomo-Bento, M. Girard, H. Maughan, D. Pittet, P. Francois, J. Schrenzel, and the GESNOMA study group. 2014. Noma affected children from Niger have distinct oral communities based on high-throughput sequencing of 16S rRNA gene fragments. PLoS Neglected Tropical Diseases 8:e3240
    6. Belcheva, A., T. Irrazabal, S.J. Robertson, C. Streutker, H. Maughan, S. Rubino, E.H. Moriyama, J.K. Copeland, A. Surendra, S. Kumar, B. Green, K. Geddes, R.C. Pezo, W.W. Navarre, M. Milosevic, B.C. Wilson, S.E. Girardin, T.M. Wolever, W. Edelmann, D.S. Guttman, D.J. Philpott, and A. Martin. 2014. Gut microbial metabolism drives transformation of msh2-deficient colon epithelial cells. Cell. 158:288-99.
    7. Whiteson, K.L., B. Bailey, M. Bergkessel, D. Conrad, L. Delhaes, B. Felts, J.K. Harris, R. Hunter, Y.W. Lim, H. Maughan, R. Quinn, P. Salamon, J. Sullivan, B.D. Wagner, and P.B. Rainey. 2014. The upper respiratory tract as a microbial source for pulmonary infections in cystic fibrosis. Parallels from island biogeography. Am J Respir Crit Care Med. 189:1309-15. 
    8. Quinn, R.A., Y.W. Lim, H. Maughan, D. Conrad, F. Rohwer, and K.L. Whiteson. 2014. Biogeochemical forces shape the composition and physiology of polymicrobial communities in the cystic fibrosis lung. MBio. 5:e00956-13.
    9. Konya, T., B. Koster, H. Maughan, M. Escobar, M.B. Azad, D.S. Guttman, M.R. Sears, A.B. Becker, J.R. Brook, T.K. Takaro, A.L. Kozyrskyj, J.A Scott, and CHILD Study Investigators. 2014. Associations between bacterial communities of house dust and infant gut. Environ Res. 131:25-30.
    10. Lim, Y.W., J.S. Evangelista III, R. Schmieder, B. Bailey, M. Haynes, M. Furlan, H. Maughan, R. Edwards, F. Rohwer, and D. Conrad. 2014. Clinical insights from metagenomic analysis of sputum samples from patients with cystic fibrosis. J Clin Microbiol. 52:425-37.
    11. Whiteson, K.L., S. Meinardi, Y.W. Lim, R. Schmieder, H. Maughan, R. Quinn, D.R. Blake, D. Conrad, and F. Rohwer. 2014. Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation. ISME J. 8:1247-58.
    12. Lim, Y.W., R. Schmieder, M. Haynes, M. Furlan, T.D. Matthews, K. Whiteson, S.J. Poole, C.S. Hayes, D.A. Low, H. Maughan, R. Edwards, D. Conrad, and F. Rohwer. 2013. Mechanistic model of Rothia mucilaginosa adaptation toward persistence in the CF lung, based on a genome reconstructed from metagenome data. PLoS ONE 8:e64285.
    13. Azad, M.B., T. Konya, H. Maughan, D.S. Guttman, C.J. Field, M.R. Sears, A.B. Becker, J.A. Scott, A.L. Kozyrskyj, and the CHILD study investigators. 2013. Infant gut microbiota and the hygiene hypothesis of allergic disease: impact of household pets and siblings on microbiota composition and diversity. Allergy, Asthma & Clinical Immunology. 9:15.
    14. Azad, M.B., T. Konya, H. Maughan, D.S. Guttman, C.J. Field, R.S. Chari, M.R. Sears, A.B. Becker, J.A. Scott, and A.L. Kozyrskyj. 2013. Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months. Can Med Assoc J. 185:385-394.
    15. Maughan, H., P.W. Wang, J. Diaz-Caballero, P. Fung, Y. Gong, S.L. Donaldson, L. Yuan, S. Keshavjee, Y. Zhang, Y.C.W. Yau, V.J. Waters, D.E. Tullis, D.M. Hwang, and D.S. Guttman. 2012. Analysis of the Cystic Fibrosis lung microbiota via Serial Illumina Sequencing of bacterial 16S rRNA hypervariable regions. PLoS ONE 7(10):e45791
    16. Maughan, H., K.S. Cunningham, P.W. Wang, Y. Zhang, M. Cypel, et al. 2012. Pulmonary bacterial communities in surgically resected noncystic fibrosis bronchiectasis lungs are similar to those in cystic fibrosis. Pulmonary Medicine, vol. 2012, doi:10.1155/2012/746358
    17. Lee, S.-J., J. Lee, K. K. Li, D. Holland, H. Maughan, D.S. Guttman, B. Yusta, and D.J. Drucker. 2012. Disruption of the Murine Glp2r Impairs Paneth Cell Function and Increases Susceptibility to Small Bowel Enteritis. Endocrinology 153:1141—1151.
    18. Maughan, H. and W.L. Nicholson. 2011. Increased fitness and alteration of metabolic pathways during Bacillus subtilis evolution in the laboratory. Appl. Environ. Microbiol. 77:4105—4018.
    19. Maughan, H. and G. Van der Auwera. 2011. Bacillus taxonomy in the genomic era finds phenotypes essential though misleading. Infect. Genet. Evol. 11:789—797.
    20. Maughan, H., L.A. Wilson, and R.J. Redfield. 2010.  Bacterial DNA uptake sequences can accumulate by molecular drive alone.  Genetics 186: 613—627
    21. Maughan, H. and R. J. Redfield. 2009.  Tracing the evolution of competence in Haemophilus influenzaePLoS ONE 4: e5854.
    22. Maughan, H. and R. J. Redfield. 2009. Extensive variation in natural competence in Haemophilus influenzaeEvolution 63: 1852—1866.
    23. Maughan, H., C. W. Birky, Jr., and W. L. Nicholson. 2009. Transcriptome divergence and the loss of plasticity in Bacillus subtilis after 6,000 generations of evolution under relaxed selection for sporulation.  J. Bacteriol. 191: 428—433.
    24. Callahan, H. S., H. Maughan, and U. K. Steiner. 2008. Phenotypic plasticity, costs of phenotypes, and costs of plasticity: Toward an integrative view.  Ann. N. Y. Acad. Sci. 1133: 44—66
    25. Maughan, H., J. Masel, C. W. Birky, Jr., and W.L. Nicholson. 2007. The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis. Genetics 177: 1—12
    26. Masel, J. and H. Maughan. 2007. Mutations leading to the loss of sporulation ability in Bacillus subtilis are sufficiently frequent to favor genetic canalization. Genetics 175: 453-457
    27. Maughan, H. 2007. Rates of molecular evolution in bacteria are relatively constant despite spore dormancy.  Evolution 61: 280-288
    28. Masel., J., O. D. King, and H. Maughan.  2007. The loss of adaptive plasticity during long periods of environmental stasis. Am. Nat. 169: 38-46
    29. Maughan, H., V. Callicotte, A. Hancock, C.W. Birky, Jr,, W.L. Nicholson, and J. Masel. 2006. The population genetics of phenotypic deterioration in experimental populations of Bacillus subtilis. Evolution 60: 686-695
    30. Birky, C.W. Jr., C. Wolf, H. Maughan, L. Herbertson, and E. Henry. 2005. Speciation and selection without sex. Hydrobiologia. 546:1-17
    31. Maughan, H., B. Galeano, and W.L. Nicholson. 2004. Novel rpoB mutations conferring rifampicin resistance on Bacillus subtilis: global effects on growth, competence, sporulation, and germination.  J. Bacteriology 186:228-2486
    32. Maughan, H., and W.L. Nicholson. 2004. Stochastic processes influence stationary phase decisions in Bacillus subtilis. J. Bacteriology 186:2212-2214
    33. Cutter, A.D., B.A Payseur, T. Salcedo, A.M. Estes, J.M. Good, E. Wood, T. Hartl, H. Maughan, et al. 2003. Molecular correlates of genes exhibiting RNAi phenotypes in Caenorhabditis elegansGenome Research 13:2651-2657
    34. Nicholson, W.L., and H. Maughan. 2002.  The spectrum of spontaneous rifampicin resistance mutations in the rpoB gene of Bacillus subtilis 168 spores differs from vegetative cells and resembles that of Mycobacterium tuberculosisJ Bacteriology 184: 4936-4940.
    35. Maughan, H., C.W. Birky, Jr., W.L. Nicholson, W.D. Rosenzweig, and R.H. Vreeland.  2002. The paradox of the “ancient” bacterium which contains “modern” protein-coding genes.  Mol. Biol. Evol. 19: 1637-1639. 
Book chapters:
    1. Maughan, H., S. Sinha, L. Wilson, and R. J. Redfield. 2008. Competence, DNA Uptake and Transformation in Pasteurellaceae. In: Pasteurellaceae: Biology, Genomics and Molecular Aspects, eds: P. Kuhnert and H. Christensen. Caister Academic Press. (All authors contributed equally).
Presentations:
Presentations to community as Cystic Fibrosis Canada fellow:
    • "What are bacteria? And, what are they doing in CF lungs?”  Presented Nov 2010, April 2011, and May 2011
    • “Microbial communities in Cystic Fibrosis lungs.” Presented Nov 2011.
Presentations at scientific conferences (past 8 years only): (P) poster; (T) talk:
    • 2012     Keystone Microbiome Conference, Keystone, CO (P): H. Maughan, P. Wang, P. Fung, Y. Gong, J. Diaz-Caballero, Y. Zhang, D. Hwang, and D. Guttman. “Ecology of the Cystic Fibrosis Lung Microbiome.”
    • 2011     International Human Microbiome Congress, Vancouver, BC (T): H. Maughan, Y. Gong, P. Fung, D.M. Hwang, and D.S. Guttman.  “Ecology and evolution of the Cystic Fibrosis lung microbiome.”
    • 2010     European Cystic Fibrosis Young Investigator Meeting in Lille, France (T & P): H. Maughan, M. Gao, P. Fung, Y. Gong, P. Wang, D. Hwang, and D.S. Guttman. “Metagenomic analysis of bacterial communities in Cystic Fibrosis lungs.”
    • 2010     Society for Molecular Biology and Evolution meeting in Lyon, France (P): H. Maughan, M. Gao, P. Fung, Y. Gong, P. Wang, D. Hwang, and D.S. Guttman. “Ecology and evolution of the Cystic Fibrosis lung microbiome.”
    • 2008     Society for Molecular Biology and Evolution meeting in Barcelona, Spain (P): H. Maughan and R. J. Redfield.  “Do bacteria care if they recombine the DNA they take up?”
Fellowships, Grants and Awards:
    • Canadian Institutes for Health Research Emerging Team Grant: Canadian Microbiome Initiative (2010-2015)
    • Cystic Fibrosis Canada Postdoctoral Fellowship (2010-2012)
    • NIH-NRSA Kirschstein Postdoctoral Fellowship (2006-2009)
    • Honorary Killam Postdoctoral Fellow, U. of British Columbia (2006-2008)
    • Michael A. Cusanovich Dissertation Fellowship, U. of Arizona (2005-2006)
    • Women in Science and Engineering Travel Grant, U. of Arizona (2005)
    • Ernst Mayr Award, Society for Systematic Biologists (2005)
    • National Science Foundation Doctoral Dissertation Improvement Grant (2004-2006)
    • Sigma Xi Grant in Aid of Research (2004 & 2005)
    • American Society for Microbiology Corporate Partner Travel Grant  (2003)
    • National Science Foundation Integrative Graduate Education and Research Traineeship Program (IGERT) Fellowship in Genomics (2002-2004)
Society memberships: American Association for the Advancement of Science, Canadian Science Writers' Association, American Society for Microbiology, International Society for Microbial Ecology
Volunteer content review for science journals: African Journal of Biotechnology; Applied and Environmental Microbiology; Archives of Microbiology; Evolution; Infection, Genetics and Evolution; Journal of Bacteriology; Microbiology; Molecular Biology and Evolution; Molecular Ecology; National Science Foundation; PLoS ONE; US Army Research Office

References available upon request